ABOUT US

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O3 Plus, LLC was formed in February 2014 to be a catalyst for increased knowledge and awareness about Medical Ozone and its uses in health, wellness and research. The founding doctor of O3 Plus is Francis W. Mueller, MD, (“Dr. Frank”) who has been practicing family medicine in San Antonio since 1986.

In January 2016, Dr. Frank, along with Kimberly Engelman, RNC, FNP-BC, opened O3 Plus, LLC, an ozone therapy clinic, for the treatment of autoimmune, viral and other infectious diseases. He and his team of professionals are excited to be able to bring the healing attributes of ozone therapy to South Texas. His vision is to spearhead further research and acceptance of ozone therapy in mainstream American medicine.

Kimberly Engelman
MSN, APRN, FNP-BC

Classes | Workshops | Conferences

  • Ozone Therapy Training and Certification Course by Dr. Frank Shallenberger | April 2015 & January 2016
  • Beginning Prolozone® Course by Dr. Frank Shallenberger | April 2015
  • Advanced Prolozone® Course by Dr. Frank Shallenberger | September 2015
  • American Academy for the Advancement of Medicine (ACAM) Annual Meeting | November 2015
  • ACAM Basic Chelation Therapy Certification Course | November 2015
  • Methods of Ozone Therapy, Prolozone®, and Hyperbaric Ozone Autohemotherapy workshops by Dr. Robert Rowen and Dr. Terri Su. Included instruction on Zotzmann Hyperbaric Ozone Generator by Dr. Wolfgang Zotzmann and Lahodny Ozone High Dose Therapy by Dr. Johann Lahodny. Also included presentation on Direct IV Ozone by Dr. Howard Robbins | February 2016
  • American Academy of Ozonotherapy Annual Meeting | February 2016
  • Society of Progressive Medical Education Annual Conference (SOPMED) | June 2016
  • Aesthetic Ozone Workshop with Dr. Adriana Schwartz. Included instruction on treatments of acne, cellulite, alopecia, facial injections, and PRP | June 2016
  • ACAM Advanced IV Nutrients Therapy Workshop | September 2016
  • Women and Autoimmune Disease Course | October 2016
  • Frontiers in Ozone Conference | November 2016
  • Cosmetic Ozone Course by Dr. Marcelo Valio. Included instruction on localized fat, cellulite, hair, and facial rejuvenation | November 2016
  • Neural Therapy: Injection Therapies for Healing by Dr. Jeff Harris, N.D. | February 2017
  • Dr Dietrich Klinghardt’s Healing with Injections: European Techniques including Neural Therapy, Prolotherapy, Ozone and Scars. | April 2017
  • American Academy of Ozone Therapy Annual Meeting | May 2017
  • Society of Progressive Medical Education Annual Conference (SOPMED) | June 2017
  • Mercola on Energy featuring Drs Joe Mercola and Dan Pompa: BioHacking the Mitochondria | June 2017
  • Dr Frank Shallenberger’s Tools and Clinical Pearls: A Collection of 30 years of Knowledge | August 2017
  • Frontiers of Ozone Annual Meeting | November 2017
  • Stem Cells and Autologous Therapies with Ozone Including CGF, PRP, CD34+, Mesotherapy/ Cosmetic/ Hair with  Dr Ruhi Cakir | November 2017
  • Stem Cells and Autologous Therapies with Ozone Including CGF, PRP, CD34+, Mesotherapy/ Cosmetic/ Hair with  Dr Ruhi Cakir | November 2017
  • Ozone Without Borders Medical Ozone Conference | April 2018
  • American Academy of Ozone Therapy Annual Meeting | May 2018
  • Society of Progressive Medical Education Annual Conference (SOPMED) | June 2018
  • Cosmetic PRP/Ozone Workshop with Dr McMonagle | June 2018
  • Texas Nurse Practitioners Annual Conference | September 2018
  • Research Genetics Cancer Center (RGCC) Two Day Seminar with Dr Papasotiriou | September 2018
  • Cosmetic PRP with Ozone Seminar with Hands-on Training with Dr McMonagle &  Dr Bourgeois | October 2018
  • Ozone Without Borders Annual Medical Ozone Conference | April 2019
  • American Academy of Ozone Therapy Annual Meeting | May 2019
  • Society of Progressive Medical Education Annual Conference (SOPMED) | June 2019
  • Exosomes Training and Education with Duncan Ross, MD | July 2019
  • Texas Nurse Practitioners Annual Conference | September 2019
  • Applying Functional Medicine in Clinical Practice (AFMCP)Institute for Functional Medicine | September 2019
  • Chelation Advanced Provider Workshop, American College for the Advancement in Medicine (ACAM) | October 2019
  • American College for the Advancement in Medicine (ACAM) Annual Meeting: Collaborative Cures | October 2019
  • North American Academy of Neural Therapy ’s (NAANT) International Neural Therapy Congress | February 2020
  • Empire Medical Thread Lift I & II | September 2020
  • A4M Annual World Congress: The Science of Longevity Online Event | December 2020
  • Empire Medical Peptide Therapies Treatment Training | December 2020
  • Empire Medical Botulinum Toxin Training | January 2021
  • Age Management Medicine Group (AAMG) BHRT Practical Clinical Applications | April 2021
  • American Academy of Ozonotherapy Annual Meeting | May 2021
  • RHP/EBOO Training with Professor Peter Jovanovic and Dr. Vicky | October 2021
  • Frontiers of Ozone Annual Meeting | November 2021
  • Age Management Medicine Group (AAMG) 32nd Clinical Applications for Age Management Medicine Conference | April 2022
  • American Academy of Ozonotherapy Annual Meeting | June 2022
  • Qigeneration 2 Day Training to operate QiLaser System for VSEL procedures with Dr Todd Ovokaitys | August 2022
  • Texas Nurse Practitioners Annual Conference | September 2022
  • American College for the Advancement in Medicine (ACAM) Annual Meeting: Collaborative Cures | November 2022
  • Dr. Ahvie Herskowitz, President of ACAM, and Dr. Frank Shallenberger’s EBOO Workshop | November 2022
  • American Academy of Ozonotherapy Annual Meeting | May 2023
    Speaker: Ozone Case Studies: Protocols with RHP/EBOO; Low Dose Ozone including Chronic Dry Eye; Peptide Injections; and other tips from the ‘Ozone Emporium’
  • IntellxxDNA™ Annual Conference on Applied Genomics |July 2023
  • Frontiers of Ozone Annual Meeting | November 2023
    Co-Instructor of Workshop: Introduction into Cosmetic Ozone with PRP
  • American Academy of Anti Aging Medicine (a4m) World Congress Longevity Fest | December 2023
  • North American Academy of Neural Therapy ’s (NAANT) International Neural Therapy Congress| April 2024
  • NAANT Advanced Neural Therapy Hands-on Workshop | April 2024
  • American Academy of Ozonotherapy Annual Meeting | May 2024
    Speaker: Update on Ultraviolet and Polychromatic Blood Irradiation

     

    American College for the Advancement in Medicine (ACAM) 50th Anniversary Meeting | May 2024

     

    Texas Nurse Practitioners Annual Conference | September 2024

     

    Frontiers of Ozone Annual Meeting | November 2024

     

    American Academy of Anti Aging Medicine (a4m) World Congress Longevity Fest | December 2024

Memberships

  • American Academy for the Advancement of Medicine (ACAM)
  • American Academy of Ozonotherapy (AAOT): Active Fellow
  • American Association of Nurse Practitioners (AANP)
  • Institute of Functional Medicine (IFM)
  • North American Academy of Neural Therapy (NAANT)
  • Ozone Without Borders, Society for the Advancement of Bio-Oxidative Therapy: Founding Member
  • San Antonio Nurses in Advanced Practice (SANAP)
  • Texas Nurse Practitioners (TNP)

Education

  • Bachelor of Science in Communications, Radio-Television-Film, from the University of Texas in Austin, 1997
  • Registered Nurse (RN) at Baptist School of Health Professions in San Antonio, 2007
  • Bachelor of Science in Nursing from Texas Tech University Health Sciences Center (TTUHSC) School of Nursing, 2010
  • Certified in In-Patient Obstetrics by the National Certification Corporation, RNC-OB, 2010
  • Master of Science in Nursing (MSN) from Texas A&M in Corpus Christi, 2013
  • Certified as a Family Nurse Practitioner by the American Nurses Credentialing Center, 2013

Frank Mueller
M.D.

Dr. Frank is pioneer and researcher in this new field of medical ozone, although his medical degree and background are in traditional medicine.

Education

  • Completed pre-medical studies at St. Mary’s University in San Antonio
  • Graduated with a Doctor of Medicine (M.D.) from Texas Tech University Health Sciences Center (TTUHSC) School of Medicine, 1983
  • Board Certified in Family Medicine, 1986
  • Earned designation as a Castle Connolly “Top Doctor,” 2011-2014
  • Became a Fellow of the American Academy of Ozonotherapy, 2014

Dr. Frank practiced traditional medicine for 27 years. In February 2013, at the urging of his uncle, William R. Mueller, DDS, he attended the first inaugural International Academy of Ozone in Healthcare and Dentistry (IAOHD) meeting in Las Vegas.

Dr. Frank describes the inaugural IAOHD convention in his own words:

I was blown away! Here you had doctors from all over the world — Germany, Egypt, Cuba, South America, England, and the US — all using this natural substance [ozone] for decades — which I had never learned about in medical school — and all getting amazing results on a wide variety of conditions with nearly no side-effects. These conditions included some of the toughest we face in medicine: chronic fatigue, fibromyalgia, auto-immune diseases, cancer, degenerative arthritis, etc. I could not pull myself away from hearing the incredulous stories and research. If ozone could add so much to areas where traditional medicine was lacking, we could make a quantum leap forward in medical care by learning and using it properly.

Since then, Dr. Frank has taken ozone courses taught by Dr. Frank Shallenberger, Dr. Bill Domb, Dr. Howard Robins, Dr. Robert Rowen, and Dr. Sylvia Menendez of Cuba.